Scholarly output

Publications

61 publications including journal articles and book chapters, spanning nutrition, metabolism, ageing, and reproductive biology.

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Top five publications
01
Nature Metabolism · 2019
Branched-chain amino acids impact health and lifespan indirectly via amino acid balance and appetite control
Solon-Biet SM, Cogger VC, Pulpitel T, Wahl D, Clark X, et al.
DOI: 10.1038/s42255-019-0059-2
02
Cell Metabolism · 2016
Defining the nutritional and metabolic context of FGF21 using the Geometric Framework
Solon-Biet SM, Cogger VC, Pulpitel T, Heblinski M, Wahl D, McMahon AC, et al.
Cell Metabolism 24(4):555–565
03
PNAS · 2015
Macronutrient balance, reproductive function and lifespan in aging mice
Solon-Biet SM*, Walters KA* et al. — *Co-first author
PNAS 112:3481–3486
04
Cell Reports · 2015
Dietary protein to carbohydrate ratio and caloric restriction: comparing metabolic outcomes in mice
Solon-Biet SM, Mitchell SJ, Coogan SCP, Cogger VC, et al.
Cell Reports 11:1–6
05
Cell Metabolism · 2014
The ratio of macronutrients, not caloric intake, dictates cardiometabolic health, aging, and longevity in ad libitum-fed mice
Solon-Biet SM, McMahon AC, Ballard JWO, et al.
Cell Metabolism 19:418–430
2026 2 articles
6
The effect of supplementation of branched-chain amino acids by itself or combined with tryptophan or methionine on appetite control and related health outcomes in individuals aged 65–80: a randomized controlled trial protocol
Zhang S, Riberio R, Raubenheimer D, Caillaud C, Tan J, Solon-Biet SM, Cistulli P, Simpson SJ.
JMIR Research Protocols DOI: 10.2196/82436
7
Distinct macronutrient ratios optimise offspring survival, growth, and maternal glucose tolerance across mouse reproduction
Morland F, Malcolm M, Wilkinson L, Neyt C, Grattan D, Brandon A, Simpson S, Senior A, Solon-Biet SM, Terry T, Garratt M.
PNAS DOI: 10.1073/pnas.2513044123
2025 2 articles
8
Maternal nutrition can rapidly rescue a nephron deficit in low birthweight offspring
Cullen-McEwen L, Gazzard S, Goncalves G, Rose A, Eliades J, de Zoysa N, Moreau J, Hayatudin R, Solon-Biet SM, Wu Y, et al.
NPJ Metabolic Health and Disease 3:45
9
Dietary macronutrient content and energy intake in the mouse: hedonic or homeostatic override?
Simpson SJ, Senior AM, Solon-Biet SM, Le Couteur DG, Raubenheimer D.
Obesity DOI: 10.1002/oby.24312
2024 5 articles
10
Mice regulate dietary amino acid balance and energy intake by selecting between complementary protein sources
Zaman K, Mun H, Solon-Biet SM, Senior A, Raubenheimer D, Simpson SJ, Conigrave AD.
Journal of Nutrition 154(6):1766–1780
11
The relationship between dietary macronutrient composition and telomere length among US adults
Koemel N, Laouali N, Senior AM, Celermajer D, Grech A, Solon-Biet SM, Simpson SJ, Raubenheimer D, Gill TP, Skilton MR.
Advanced Biology 16:e2300619
12
The effects of paternal dietary fat versus sugar on offspring body composition and anxiety-related behaviour
Freire T, Pulpitel T, Clark X, Mackay F, Raubenheimer D, Simpson SJ, Solon-Biet SM, Crean AJ.
Physiology and Behaviour 279:114533
13
Maternal macronutrient intake effects on offspring macronutrient targets and metabolism
Freire T, Clark X, Pulpitel T, Bell-Anderson K, Ribeiro R, Raubenheimer D, Crean AJ, Simpson SJ, Solon-Biet SM.
Obesity 32:4
14
Does diet influence aging? Evidence from animal studies
Le Couteur DG, Raubenheimer DR, Solon-Biet SM, de Cabo R, Simpson SJ.
Journal of Internal Medicine DOI: 10.1111/joim.13530
2023 1 article
15
Toward reconciling the roles of FGF21 in protein appetite, sweet preference and energy expenditure
Solon-Biet SM, Clark X, Bell-Anderson K, Rusu PM, Perks R, Freire T, Pulpitel T, Senior AM, Hoy AJ, Aung O, Le Couteur DG, Raubenheimer D, Rose AJ, Conigrave AD, Simpson SJ.
Cell Reports 42:113536
2022 4 articles
16
The quality of energy- and macronutrient-balanced diets regulates host susceptibility to influenza in mice
Cootes TA, Bhattacharyya ND, Huang S, Daniel L, Bell-Anderson K, Stifter SA, Chew T, Solon-Biet SM, et al.
Cell Reports 41:111638
17
The interplay between PCOS pathology and diet on gut microbiota in a mouse model
Rodriguez Paris V, Wong XY, Solon-Biet SM, Edwards MC, Aflatounian A, Gilchrist R, Simpson SJ, Handelsman DJ, Kaakoush NO, Walters K.
Gut Microbes 14:1
18
Dietary balance across the life course: an integrative approach
Raubenheimer D, Senior AM, Mirth C, Cui Z, Hou R, Le Couteur DG, Solon-Biet SM, Leopold P, Simpson SJ.
iScience 25:104315
19
Meta-analysis links dietary branched-chain amino acids to metabolic health in rodents
Solon-Biet SM, Griffiths L, Fosh S, Le Couteur DG, Simpson SJ, Senior AM.
BMC Biology 20:1
2021 4 articles
20
The impacts of chronic consumption of low dietary protein on kidney function and structure are not explained by traditional kidney disease risk factors
Fotheringham A, Solon-Biet SM, Bielefeldt-Ohmann H, McCarthy D, McMahon A, et al.
iScience 24:11
21
Long-term nutritional regulation of liver proteome targets the spliceosome and mitochondria in mice
Le Couteur D, Solon-Biet SM, Parker BL, Pulpitel T, Brandon A, Hunt N, et al.
Cell Metabolism 32:12
22
Impact of dietary carbohydrate type and protein–carbohydrate interaction on metabolic health
Wali J, Milner A, Luk A, Pulpitel T, Dodgson T, Facey H, Wahl D, Kebede M, Senior A, Brandon A, Yau B, Solon-Biet SM, et al.
Nature Metabolism DOI: 10.1038/s42255-021-00393-9
23
Macronutrient determinants of obesity, insulin resistance and metabolic health
Wali J, Solon-Biet SM, Freire T, Brandon AE.
Biology 10:336
2020 6 articles
24
LC-N2G: a local consistency approach for nutrigenomics data analysis
Xu X, Solon-Biet SM, Senior A, Raubenheimer D, Simpson SJ, Fontana L, Mueller S, Yang JYH.
BMC Bioinformatics 21:530
25
Branched chain amino acids, aging and age-related health
Le Couteur DG, Solon-Biet SM, Cogger VC, Ribeiro R, de Cabo R, Raubenheimer D, Cooney GJ, Simpson SJ.
Ageing Research Reviews 64:101198
26
Defining the impact of dietary macronutrient balance on PCOS traits
Rodriguez Paris V, Solon-Biet SM, Senior AM, Edwards MC, et al.
Nature Communications 11:5262
27
Restriction of essential amino acids dictates the systemic metabolic response to dietary protein dilution
Yap YY, Rusu PM, Chan AY, Fam BC, Jungmann A, Solon-Biet SM, et al.
Nature Communications 11:2894
28
Sex-specific metabolic responses to 6 hours fasting during the active phase in young mice
Freire T, Senior A, Perks R, Pulpitel T, Clark X, Brandon A, Wahl D, Hatchwell L, Le Couteur D, Cooney G, Larance M, Simpson S, Solon-Biet SM.
Journal of Physiology DOI: 10.1113/JP278806
29
The geometric framework reveals that a moderate-protein, high carbohydrate intake is optimal for severe burn injury in mice
Hew J, Parungao R, Shi PH, Tsai K, Ma D, Nicholls C, Li Z, Solon-Biet SM, D'Souza M, Le Couteur D, Simpson SJ, et al.
British Journal of Nutrition
2019 7 articles
30
Of older mice and men: branched-chain amino acids and body composition
Ribeiro R*, Solon-Biet SM*, Pulpitel T, Senior A, Cogger V, Clark X, et al. — *Co-first author
Nutrients13:11(8)
31
Aging, lifestyle and dementia
Wahl D, Solon-Biet SM, Cogger VC, Fontana L, Simpson SJ, Le Couteur DG, Ribeiro RV.
Neurobiology of Disease130:104481
32
Dietary macronutrient content, age-specific mortality and lifespan
Senior AM, Solon-Biet SM, Cogger VC, Le Couteur DG, Nakagawa S, Raubenheimer D, Simpson SJ.
Proceedings of the Royal Society B DOI: 10.1098/rspb.2019.0393
33
FGF21 signals protein status to the brain and adaptively regulates food choice and metabolism
Hill CM, Laeger T, Dehner M, Albarado DC, Clarke B, Wanders D, Burke SJ, Solon-Biet SM, Simpson SJ, et al.
Cell Reports27:2934–2947
34
Central nervous system SIRT1 expression is required for cued and contextual fear conditioning memory responses in aging mice
Wahl D, Gokarn R, Mitchell SJ, Solon-Biet SM, Cogger VC, Simpson SJ, Le Couteur DG, de Cabo R.
Nutrition and Healthy Aging DOI: 10.3233/NHA-180059
35
Ingestion of resistant starch by mice markedly increases microbiome-derived metabolites
Koay YC, Wali JA, Luk AWS, Macia L, Cogger VC, Pulpitel TJ, Wahl D, Solon-Biet SM, Holmes A, Simpson SJ, O'Sullivan JF.
FASEB J
36
Sucrose and starch intake contribute to alveolar bone height in a rodent model of naturally occurring periodontitis
Morimoto J, Senior A, Ruiz K, Wali J, Pulpitel T, Solon-Biet SM, Cogger V, Raubenheimer D, Le Couteur DG, Simpson SJ, Eberhard J.
PLoS One14:e0212796
2018 6 articles
37
The Geometric Framework: an approach for studying the impact of nutrition and healthy aging
Solon-Biet SM, Wahl D, Raubenheimer D, Cogger VC, Le Couteur DG, Simpson SJ.
Drug Discovery Today: Disease Models
38
Comparing the effects of low protein, high carbohydrate diets and caloric restriction on brain aging in mice
Wahl D, Solon-Biet SM, Wang QP, Wali JA, Pulpitel T, Clark X, et al.
Cell Reports25:2234–2243
39
Effects of temperature on macronutrient selection, metabolic and swimming performance of the Indo-Pacific Damselfish
Rowe C, Figueira W, Raubenheimer D, Solon-Biet SM, Machovsky-Capuska GE.
Marine Biology 165:178
40
Long-term dietary macronutrients and hepatic gene expression in aging mice
Gokarn R, Solon-Biet SM, Cogger VC, Cooney GC, Wahl D, McMahon AC, et al.
Journal of Gerontology: Biological Sciences DOI: 10.1093/gerona/gly065
41
Nutritional geometry of liver disease including non-alcoholic fatty liver disease
Simpson SJ, Raubenheimer D, Cogger VC, Macia L, Solon-Biet SM, Le Couteur DG, George J.
Journal of Hepatology62:316–325
42
The relationship between dietary macronutrients and hepatic telomere length in aging mice
Gokarn R, Solon-Biet SM, Youngson NA, Wahl D, Cogger VC, McMahon AC, et al.
Journal of Gerontology: Biological Sciences DOI: 10.1093/gerona/glx186
2013–2017 17 articles
43
Nutritional geometry of paternal effects on embryo mortality
Polak M, Simmons LW, Benoit JB, Ruohonen K, Simpson SJ, Solon-Biet SM.
Proceedings of the Royal Society B284(1864) · 2017
44
Cognitive and behavioral evaluation of nutritional interventions in rodent models of brain aging and dementia
Wahl D, Coogan SCP, Solon-Biet SM, de Cabo R, Haran JB, Raubenheimer D, et al.
Clinical Interventions in Aging12:1419–1428 · 2017
45
The Geometric Framework for Nutrition as a tool in precision medicine
Simpson SJ, Le Couteur DG, James DE, George J, Gunton JE, Solon-Biet SM, Raubenheimer D.
Nutrition and Healthy Aging · 2017
46
The contribution of dietary restriction to extended longevity in the malaria vector Anopheles coluzzi
Faiman R, Solon-Biet SM, Sullivan M, Huestis DL, Lehmann T.
Parasites and Vectors10:156 · 2017
47
Dietary protein, aging and nutritional geometry
Simpson SJ, Le Couteur DG, Raubenheimer D, Solon-Biet SM, Cooney GJ, Cogger VC, Fontana L.
Ageing Research Reviews · 2017
48
Diet-microbiome interactions in health are controlled by intestinal nitrogen source constraints
Holmes AJ, Chew Y, Colakoglu F, Cliff JB, Klaassens E, Read MN, Solon-Biet SM, McMahon AC, et al.
Cell Metabolism25(1):140–151 · 2017
49
The effects of dietary macronutrient balance on skin structure in aging male and female mice
Hew J*, Solon-Biet SM*, McMahon AC, et al. — *Co-first author
PLoS ONE11:e0166175 · 2016
50
Nutritional strategies to optimise cognitive function in the aging brain
Wahl D, Cogger VC, Solon-Biet SM, et al.
Ageing Research Reviews31:80–92 · 2016
51
Nutritional ecology and the evolution of aging
Raubenheimer D, Simpson SJ, Le Couteur DG, Solon-Biet SM, Coogan SCP.
Experimental Gerontology86:50–61 · 2016
52
Ultrastructure of the liver microcirculation influences hepatic and systemic insulin activity and provides a mechanism for age-related insulin resistance
Mohamad M, Mitchell SJ, Wu LE, White MY, Cordwell SJ, Mach J, Solon-Biet SM, et al.
Aging Cell15(4):706–15 · 2016
53
New Horizons: Dietary protein, ageing and the Okinawan ratio
Le Couteur DG, Solon-Biet SM, Wahl D, Cogger VC, et al.
Age and Ageing45(4):443–7 · 2016
54
Dietary macronutrients and the aging liver sinusoidal endothelial cell
Cogger VC, Mohamad M, Solon-Biet SM, Senior A, Warren A, et al.
American Journal of Physiology Heart and Circulatory Physiology310(9):H1064–70 · 2016
55
The impact of low-protein high-carbohydrate diets on aging and lifespan
Le Couteur DG, Solon-Biet SM, Cogger VC, Mitchell SJ, Senior A, de Cabo R, Raubenheimer D, Simpson SJ.
Cellular and Molecular Life Sciences73(6):1237–52 · 2016
56
Macronutrients and caloric intake in health and longevity
Solon-Biet SM, Mitchell SJ, De Cabo R, Raubenheimer D, Le Couteur DG, Simpson SJ.
Journal of Endocrinology226:R17–R28 · 2015
57
The influence of macronutrients on splanchnic and hepatic lymphocytes in aging mice
Le Couteur D, Tay S, Solon-Biet SM, Bertolino P, McMahon AC, et al.
Journal of Gerontology: Biological Sciences196:1–9 · 2014
58
Liver aging and pseudocapillarization in a Werner syndrome mouse model
Cogger VC, Svistounov D, Warren A, Zykova S, Melvin RG, Solon-Biet SM, et al.
Journals of Gerontology Series A69(9):1076–86 · 2014
59
Effects of dietary protein to carbohydrate balance on energy intake, fat storage, and heat production in mice
Huang X, Hancock DP, Gosby AK, McMahon AC, Solon SM, Le Couteur DG, et al.
Obesity21:85–92 · 2013
Book chapters 2 chapters
60
Modelling nutrition and brain aging in rodents
Wahl D, Gokarn R, Solon-Biet SM, Cogger VC, LaRocca T, Raubenheimer D, Simpson SJ, Le Couteur DG.
The Neuroscience of Aging · Elsevier, New York · 2020 Book chapter
61
A framework for uncovering the roles of calories and macronutrients in health and aging
Solon-Biet SM, Wahl D, Raubenheimer D, Le Couteur DG, Simpson SJ, Cogger VC.
Conn's Handbook on Models for Human Aging, Ch. 85 · Elsevier, New York · 2018 Book chapter